This is a
previous iteration where we review information related to
maintaining healthy joints
Joint Facts
There are 3 joint classifications; cartilagenous, fibrous and
synovial.
There are 6 types of synovial joint articulations in the human
body.
The gas present in synovial joint fluid in the hand has been found
to be over 80% CO2.
Health Tips
How do you safely protect your family from E. coli, Samonella,
and Shigella, spp. while disinfecting the kitchen?
Susan Sumner, a food scientist at Virginia Polytechnic Institute
and State University, worked out the recipe for just such a
sanitizing combo.
Just purchase 3% hydrogen peroxide and plain white vinegar and a
pair of brand new clean sprayers. Spray your fruit and vegis with
both then rinse well under running water.
It also works well for sanitizing cutting boards and kitchen
counters.
In tests run at Virginia Polytechnic Institute and State
University, pairing the two mists killed virtually all Salmonella,
Shigella, or E. coli bacteria on heavily contaminated food and
surfaces when used in this fashion, making this spray combination
more effective at killing these potentially lethal bacteria than
chlorine bleach or any commercially available kitchen cleaner.
Joint Health
These days, everyone is doing their best to maintain proper health
of their joints. These joints include knee, elbow, ankle, and more
frequently joints in the spine. But what is an appropriate measure
to maximize the life of your joints? To help put things into
perspective, we have reviewed articles published in respected,
peer-reviewed health and medical journals.
Glucosamine and
chondroitin for treatment of osteoarthritis: a systematic quality
assessment and meta-analysis.
McAlindon TE, LaValley MP, Gulin JP, Felson DT.
The Arthritis Center, Boston University School of Medicine, Mass
02118, USA.
JAMA. 2000 Mar 15;283(11):1483-4
CONTEXT: Glucosamine and chondroitin preparations are widely touted
in the lay press as remedies for osteoarthritis (OA), but
uncertainty about their efficacy exists among the medical community.
OBJECTIVE: To evaluate benefit of glucosamine and chondroitin
preparations for OA symptoms using meta-analysis combined with
systematic quality assessment of clinical trials of these
preparations in knee and/or hip OA. DATA SOURCES: We searched for
human clinical trials in MEDLINE (1966 to June 1999) and the
Cochrane Controlled Trials Register using the terms osteoarthritis,
osteoarthrosis, degenerative arthritis, glucosamine, chondroitin,
and glycosaminoglycans. We also manually searched review articles,
manuscripts, and supplements from rheumatology and OA journals and
sought unpublished data by contacting content experts, study
authors, and manufacturers of glucosamine or chondroitin. STUDY
SELECTION: Studies were included if they were published or
unpublished double-blind, randomized, placebo-controlled trials of 4
or more weeks' duration that tested glucosamine or chondroitin for
knee or hip OA and reported extractable data on the effect of
treatment on symptoms. Fifteen of 37 studies were included in the
analysis. DATA EXTRACTION: Reviewers performed data extraction and
scored each trial using a quality assessment instrument. We computed
an effect size from the intergroup difference in mean outcome values
at trial end, divided by the SD of the outcome value in the placebo
group (0.2, small effect; 0.5, moderate; 0.8, large), and applied a
correction factor to reduce bias. We tested for trial heterogeneity
and publication bias and stratified for trial quality and size. We
pooled effect sizes using a random effects model. DATA SYNTHESIS:
Quality scores ranged from 12.3% to 55.4% of the maximum, with a
mean (SD) of 35.5% (12%). Only 1 study described adequate allocation
concealment and 2 reported an intent-to-treat analysis. Most were
supported or performed by a manufacturer. Funnel plots showed
significant asymmetry (P< or =.01) compatible with publication
bias. Tests for heterogeneity were nonsignificant after removing 1
outlier trial. The aggregated effect sizes were 0.44 (95% confidence
interval [CI], 0.24-0.64) for glucosamine and 0.78 (95% CI,
0.60-0.95) for chondroitin, but they were diminished when only
high-quality or large trials were considered. The effect sizes were
relatively consistent for pain and functional outcomes. CONCLUSIONS:
Trials of glucosamine and chondroitin preparations for OA symptoms
demonstrate moderate to large effects, but quality issues and likely
publication bias suggest that these effects are exaggerated.
Nevertheless, some degree of efficacy appears probable for these
preparations.
What does this mean? This is a landmark article in a highly
respected medical journal generally pointing to an effectiveness of
glucosamine sulfate or chondroitin sulfate for the treatment of
osteoarthritis symptoms. It is an assimilation of retrospective data
and does not present original information on glucosamine's molecular
mechanisms. Should you be taking Glucosamine sulfate and chondroitin
sulfate? Talk to our doctor
of chiropractic.
Other articles that suggest a benefit of glucosamine sulfate usage
for osteoarthritis in the knee, and in the TMJ include the
following.
Reginster JY, Deroisy R, Rovati LC, Lee RL, Lejeune E, Bruyere O,
Giacovelli G, Henrotin Y, Dacre JE, Gossett C. Long-term effects of
glucosamine sulphate on osteoarthritis progression: a randomised,
placebo-controlled clinical trial. Lancet 2001 Jan
27;357(9252):251-6.
Thie NM, Prasad NG, Major PW. Evaluation of glucosamine sulfate
compared to ibuprofen for the treatment of temporomandibular joint
osteoarthritis: a randomized double blind controlled 3 month
clinical trial. J Rheumatol 2001 Jun;28(6):1347-55.